DG1 (Compound 8Nc) is a Thymidylate Synthase inhibitor that disrupts angiogenesis and metabolic reprogramming in NSCLC cells, suppressing CD26, ET-1, FGF-1, and EGF expression. It has demonstrated potent anti-proliferative efficacy in both in vitro studies and an A549 xenograft mouse model.
Molecular Weight:
427.43
Formula:
C19H17N5O5S
Target:
DNA/RNA Synthesis,Others
* VAT and and shipping costs not included. Errors and price changes excepted