HDAC6-IN-17 (5b) is a selective HDAC6 inhibitor with an IC50 of 150 nM, showing over 9-fold selectivity against HDAC8 and HDAC4. This compound exhibits cytotoxic effects in human cancer cell lines and is a valuable chemical probe for studying HDAC6 biology in oncology research, including in vitro mechanism-of-action studies.
Molecular Weight:
403.45
Formula:
C22H17N3O3S
Target:
HDAC
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