anti-retroviral, Asn126, diphenylpyrazolo, Human immunodeficiency virus, HIV, HIV Protease, HIV-1 Nef, HIVProtease, Hck, Hck IN 1, HckIN1, Hck-IN-1, Inhibitor, inhibit, Nef, Nef:Hck, Nef-dependent, Src, replication
Hck-IN-1 is a selective small molecule antagonist of the HIV-1 Nef protein, potently inhibiting the Nef:Hck interaction and wild-type HIV-1 replication in vitro. It serves as a valuable chemical probe for studying Nef-dependent signaling in host cells and viral pathogenesis, with applications in retrovirology and antiretroviral drug discovery research.
Molecular Weight:
402.81
Purity:
99.07% (May vary between batches)
CAS Number:
[1473404-51-1]
Formula:
C16H11ClN6O3S
Target:
Hck,Src,HIV Protease
Application Notes:
Solubility: DMSO:12.5 mg/mL (31.03 mM)
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