hGPR91 antagonist 1 is a highly potent and selective inhibitor of the human GPR91 receptor, demonstrating an IC50 of 7 nM. This compound is a valuable research tool for investigating the role of succinate signaling in metabolic disorders, diabetic retinopathy, and hypertension using both cellular and animal models.
Molecular Weight:
529.53
Purity:
99.85% (May vary between batches)
CAS Number:
[1314796-00-3]
Formula:
C31H23F4N3O
Target:
Succinate Receptor 1 (SUCNR1)
Application Notes:
Solubility: DMSO:25 mg/mL (47.21 mM)
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