iFSP1 is a potent and selective FSP1 (AIFM2) inhibitor with an EC50 of 103 nM, functioning independently of glutathione. It sensitizes cancer cells to ferroptosis inducers like RSL3 and uniquely induces ferroptosis in GPX4-knockout, FSP1-overexpressing cells, making it a valuable tool for investigating ferroptosis pathways in vitro.
Molecular Weight:
323.35
Purity:
99.74% (May vary between batches)
CAS Number:
[150651-39-1]
Formula:
C20H13N5
Target:
Ferroptosis
Application Notes:
Solubility: DMSO:25 mg/mL (77.32 mM)
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