JR AB2 011, JRAB2011, JR-AB-2-011, JR-AB2-011, mTORC2
JR-AB2-011 is a potent and selective mTORC2 inhibitor (IC50 = 0.36 µM) that acts by disrupting the Rictor-mTOR interaction (K = 0.19 µM). It demonstrates cytotoxic effects in glioblastoma cell models, making it a valuable research tool for studying mTORC2 signaling in cancer biology, both in vitro and in vivo.
