Eltanexor, CAS [[1642300-52-4]]
Catalog Number:
BYT-ORB1309507
Product Overview
Article Name:
Eltanexor, CAS [[1642300-52-4]]
Biozol Catalog Number:
BYT-ORB1309507
Supplier Catalog Number:
orb1309507
Alternative Catalog Number:
BYT-ORB1309507-1, BYT-ORB1309507-1, BYT-ORB1309507-10, BYT-ORB1309507-100, BYT-ORB1309507-200, BYT-ORB1309507-25, BYT-ORB1309507-5, BYT-ORB1309507-50
Manufacturer:
Biorbyt
Category:
Biochemikalien
Alternative Names:
ATG 016, ATG016, ATG-016, Eltanexor, KPT8602, KPT-8602, KPT 8602, ONO7706, ONO-7706, ONO 7706, XPO1
Product Description
Eltanexor (ONO-7706) is an orally bioavailable, potent inhibitor of exportin-1 (XPO1) with an EC50 of 60.9 nM. It induces caspase-dependent apoptosis in leukemic cell lines and has demonstrated anti-leukemic activity in preclinical in vitro and in vivo research models.
Product Properties
Molecular Weight:
428.29
Purity:
99.86% (May vary between batches)
CAS Number:
[1642300-52-4]
Formula:
C17H10F6N6O
Target:
CRM1,Others
Application Notes
Application Notes:
Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.71 mM),DMSO:80 mg/mL (186.79 mM),H2O:< 0.1 mg/mL (insoluble)
