LEQ506 is a potent and selective small molecule inhibitor of Smoothened (Smo), demonstrating IC50 values of 2 nM for human and 4 nM for mouse Smo. It is a valuable research tool for investigating Hedgehog signaling pathway biology in both in vitro cellular assays and in vivo preclinical models.
Molecular Weight:
432.56
Purity:
99.76% (May vary between batches)
CAS Number:
[1204975-42-7]
Formula:
C25H32N6O
Target:
Smo
Application Notes:
Solubility: DMSO:100 mg/mL (231.18 mM)
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