strain E1590, strain E1630, Bacterial, anti-bacterial, E. faecium, Inhibitor, MDR, inhibit, multidrug-resistant, LtaS IN 1, LtaSIN1, LtaS-IN-1
LtaS-IN-1 is a small molecule inhibitor of lipoteichoic acid synthesis effective against multidrug-resistant Enterococcus faecium. It demonstrates potent antibacterial activity in vitro, with MIC values from 0.5 to 64 µg/mL against various strains, by disrupting cell wall morphology. This compound is a valuable research tool for studying Gram-positive cell wall biosynthesis and novel antibiotic mechanisms.