PTC299, CAS [[1256565-36-2]]
Catalog Number:
BYT-ORB1309211
Product Overview
Article Name:
PTC299, CAS [[1256565-36-2]]
Biozol Catalog Number:
BYT-ORB1309211
Supplier Catalog Number:
orb1309211
Alternative Catalog Number:
BYT-ORB1309211-1,BYT-ORB1309211-5,BYT-ORB1309211-10,BYT-ORB1309211-25,BYT-ORB1309211-50,BYT-ORB1309211-100
Manufacturer:
Biorbyt
Category:
Biochemikalien
Alternative Names:
Dihydroorotate Dehydrogenase, DHODH, DNA/RNA Synthesis, cancer, (4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate, oral, off-target, kinase, inhibit, myelosuppression, malignancies, hematologic, Inhibitor, Emvododstat, PTC299, PTC-299, PTC 299, Vascular endothelial growth factor receptor, VEGFR
Product Description
PTC299 is an orally bioavailable small molecule that selectively inhibits VEGFA protein synthesis post-transcriptionally and potently targets dihydroorotate dehydrogenase (DHODH). It has been investigated in preclinical in vitro and in vivo studies for its potential application in angiogenesis-dependent research areas, including oncology.
Product Properties
Molecular Weight:
467.34
Purity:
99.72% (May vary between batches)
CAS Number:
[1256565-36-2]
Formula:
C25H20Cl2N2O3
Target:
DNA/RNA Synthesis,VEGFR,Dehydrogenase
Application Notes
Application Notes:
Solubility: 10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (2.14 mM),DMSO:50 mg/mL (106.99 mM)
