PT2399, CAS [[1672662-14-4]]
Catalog Number:
BYT-ORB1309175
Product Overview
Article Name:
PT2399, CAS [[1672662-14-4]]
Biozol Catalog Number:
BYT-ORB1309175
Supplier Catalog Number:
orb1309175
Alternative Catalog Number:
BYT-ORB1309175-1,BYT-ORB1309175-5,BYT-ORB1309175-10,BYT-ORB1309175-25,BYT-ORB1309175-50,BYT-ORB1309175-100
Manufacturer:
Biorbyt
Category:
Biochemikalien
Alternative Names:
Inhibitor, inhibit, Hypoxia-inducible factors, HIFs, HIF-PH, HIFProlylHydroxylase, HIF-2alpha, HIF/HIFProlylHydroxylase, HIF/HIF ProlylHydroxylase, HIF/HIF Prolyl-Hydroxylase, HIF, HIF ProlylHydroxylase, HIF Prolyl-Hydroxylase, PT2399, PT-2399, PT 2399
Product Description
PT2399 is a selective, orally bioavailable HIF-2alpha inhibitor that disrupts its dimerization with HIF-1beta. It demonstrates significant antitumor efficacy in preclinical in vivo models, making it a valuable chemical probe for researching hypoxia signaling pathways in renal cell carcinoma and other cancers.
Product Properties
Molecular Weight:
419.32
Purity:
99.45% (May vary between batches)
CAS Number:
[1672662-14-4]
Formula:
C17H10F5NO4S
Target:
HIF/HIF Prolyl-Hydroxylase,HIF
Application Notes
Application Notes:
Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (11.92 mM),DMSO:262.5 mg/mL (626.01 mM)
