RG7834 (RO 7020322) is a potent, orally bioavailable small-molecule inhibitor of hepatitis B virus, demonstrating low nanomolar IC50 values against HBsAg, HBeAg, and HBV DNA in dHepaRG cell assays. It serves as a valuable research tool for investigating HBV replication mechanisms and evaluating antiviral strategies in both in vitro and in vivo models.