Pamufetinib (TAS-115) is a dual kinase inhibitor targeting VEGFR2 and c-Met with high potency, exhibiting IC50 values of 30 nM and 32 nM, respectively. It is utilized in preclinical cancer research, including studies on angiogenesis and tumor growth in both cellular and animal models.
Molecular Weight:
518.56
Purity:
99.39% (May vary between batches)
CAS Number:
[1190836-34-0]
Formula:
C27H23FN4O4S
Target:
c-Met/HGFR,VEGFR
Application Notes:
Solubility: DMSO:13 mg/mL (25.07 mM)
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