Ubiquitination-IN-1, CAS [[1819330-15-8]]
Catalog Number:
BYT-ORB1308977
Product Overview
Article Name:
Ubiquitination-IN-1, CAS [[1819330-15-8]]
Biozol Catalog Number:
BYT-ORB1308977
Supplier Catalog Number:
orb1308977
Alternative Catalog Number:
BYT-ORB1308977-1,BYT-ORB1308977-10,BYT-ORB1308977-100,BYT-ORB1308977-25,BYT-ORB1308977-5,BYT-ORB1308977-50,BYT-ORB1308977-500
Manufacturer:
Biorbyt
Category:
Biochemikalien
Alternative Names:
inhibit, Inhibitor, interaction, E1 activating enzyme, E2 conjugating enzyme, E1/E2/E3 Enzyme, E3 ligating enzyme, degradation, Cksl, protein-protein, Skp2, suppressors, tumor, Ubiquitin activating enzyme, ubiquitination, Ubiquitination IN 1, UbiquitinationIN1, Ubiquitination-IN-1, Ubiquitin ligase, Ubiquitin conjugating enzyme
Product Description
Ubiquitination-IN-1 is a potent small molecule inhibitor that disrupts the Cks1-Skp2 interaction and inhibits ubiquitination with an IC50 of 0.17 µM. This compound is a valuable research tool for studying cell cycle regulation, protein degradation, and has been utilized in both in vitro and in vivo cancer research models.
Product Properties
Molecular Weight:
429.42
Purity:
99.88% (May vary between batches)
CAS Number:
[1819330-15-8]
Formula:
C21H14F3N3O2S
Target:
E1/E2/E3 Enzyme,Others
Application Notes
Application Notes:
Solubility: DMSO:60 mg/mL (139.72 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.66 mM)