868359-05-1, 868359-05-1 free base, Human EAAT1, Human EAAT2, Human EAAT3, WAY 213613 Hydrochloride, WAY 213613 hydrochloride, WAY-213613 hydrochloride (868359-05-1 free base), WAY213613 Hydrochloride, WAY213613 hydrochloride, WAY-213613 Hydrochloride
WAY-213613 hydrochloride is a potent and selective nonsubstrate inhibitor of the glutamate transporter EAAT2 (GLT-1), with an IC50 of 85 nM. It exhibits over 40-fold selectivity versus EAAT1 and EAAT3 and is inactive at glutamate receptors. This compound serves as a valuable pharmacological tool for studying EAAT2 function in both in vitro and in vivo models of CNS disorders.
