This small molecule inhibitor potently disrupts the HIF-1alpha and von Hippel-Lindau protein interaction with an IC50 of 2.0 µM. It is a valuable research tool for studying hypoxia signaling pathways in oncology and cardiovascular disease, applicable in both cellular and biochemical assays.
Molecular Weight:
363.41
Purity:
99.94% (May vary between batches)
CAS Number:
[117953-17-0]
Formula:
C20H21N5O2
Target:
HIF,HIF/HIF Prolyl-Hydroxylase
Application Notes:
Solubility: DMSO:7.5 mg/mL (20.64 mM)
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