NOTCH4 Recombinant Antibody, PE Conjugated, Rabbit
Biozol Catalog Number:
BSS-BSM-61337R-PE-TRIAL
Supplier Catalog Number:
bsm-61337R-PE
Alternative Catalog Number:
BSS-BSM-61337R-PE-20
Manufacturer:
Bioss
Host:
Rabbit
Category:
Antikörper
Application:
FC, WB
Species Reactivity:
Human, Mouse
Conjugation:
PE
Alternative Names:
NOTC4, hNotch4, INT3, Notch homolog 4.
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system.