ATP receptor, P2 purinoceptor subtype Y1, P2RY1, P2Y purinoceptor 1, P2Y1 purinoceptor, Platelet ADP receptor, Purinergic receptor, Purinergic receptor P2Y G protein coupled 1, Purinergic receptor P2Y1, P2RY1_HUMAN, P2Y1 purinoceptor.
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008]
