C8orf76 Polyclonal Antibody, PE Conjugated, Rabbit
Biozol Catalog Number:
BSS-BS-15301R-PE
Supplier Catalog Number:
bs-15301R-PE
Alternative Catalog Number:
BSS-BS-15301R-PE-100
Manufacturer:
Bioss
Host:
Rabbit
Category:
Antikörper
Application:
IF, WB
Species Reactivity:
Human
Conjugation:
PE
Alternative Names:
Chromosome 8 open reading frame 76, Hypothetical protein LOC84933, LOC84933, Uncharacterized protein C8orf76,CH076_HUMAN.
C8orf76 (chromosome 8 open reading frame 76) is a 380 amino acid protein encoded by a gene that maps to human chromosome 8q24.13. Consisting of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and are typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.
