TAF12 Antibody - N-terminal region

Article Name:	TAF12 Antibody - N-terminal region
Biozol Catalog Number:	ASB-P100965_P050
Supplier Catalog Number:	P100965_P050
Alternative Catalog Number:	ASB-P100965_P050-25UL,ASB-P100965_P050-100UL
Manufacturer:	Aviva
Host:	Rabbit
Category:	Proteine/Peptide
Application:	ChIP, WB
Species Reactivity:	Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
Immunogen:	The immunogen is a synthetic peptide directed towards the N terminal region of human TAF12
Alternative Names:	TAF2J, TAFII20

Control of transcription by RNA polymerase II involves the basal transcription machinery which is a collection of proteins. These proteins with RNA polymerase II, assemble into complexes which are modulated by transactivator proteins that bind to cis-regulatory elements located adjacent to the transcription start site. Some modulators interact directly with the basal complex, whereas others may act as bridging proteins linking transactivators to the basal transcription factors. Some of these associated factors are weakly attached while others are tightly associated with TBP in the TFIID complex. Among the latter are the TAF proteins. Different TAFs are predicted to mediate the function of distinct transcriptional activators for a variety of gene promoters and RNA polymerases. TAF12 interacts directly with TBP as well as with TAF2I.Control of transcription by RNA polymerase II involves the basal transcription machinery which is a collection of proteins. These proteins with RNA polymerase II, assemble into complexes which are modulated by transactivator proteins that bind to cis-regulatory elements located adjacent to the transcription start site. Some modulators interact directly with the basal complex, whereas others may act as bridging proteins linking transactivators to the basal transcription factors. Some of these associated factors are weakly attached while others are tightly associated with TBP in the TFIID complex. Among the latter are the TAF proteins. Different TAFs are predicted to mediate the function of distinct transcriptional activators for a variety of gene promoters and RNA polymerases. TAF12 interacts directly with TBP as well as with TAF2I. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Clonality:	Polyclonal
Concentration:	0.5 mg/ml
Molecular Weight:	18kDa
NCBI:	6883
Form:	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

	Quiescent human colon carcinoma HCT116 cultures were treated with 10% FBS for three time points (0, 15, 30min) or (0, 30, 60min) were used in Matrix-ChIP and real-time PCR assays at EGR1 gene (Exon1) and 15kb upstream site.
	WB Suggested Anti-TAF12 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Transfected 293TTAF12 is supported by BioGPS gene expression data to be expressed in HEK293T
	TAF12 antibody - N-terminal region (P100965_P050) in Human 293T using Western Blot