ARF exchange factor,ARF nucleotide-binding site opener,ARNO,CTC-273B12.8,CTS18,CTS18.1,cytohesin-2,PH, SEC7 and coiled-coil domain-containing protein 2,pleckstrin homology, Sec7 and coiled/coil domains 2 (cytohesin-2),pleckstrin homology, Sec7 and coiled-coil domains 2,PSCD2,PSCD2L,SEC7L,Sec7p-L,Sec7p-like.
Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Activates ARF factors through replacement of GDP with GTP (By similarity). The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane (PubMed:17398095). Involved in neurite growth (By similarity).
