Recombinant Human Serine/threonine-protein phosphatase PGAM5, mitochondrial protein (30-223AA)
Conjugation:
Unconjugated
Alternative Names:
Bcl-XL-binding protein v68,BXLBV68,PGAM family member 5, serine/threonine protein phosphatase, mitochondrial,phosphoglycerate mutase family member 5,serine/threonine-protein phosphatase PGAM5, mitochondrial.
Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore.
