Recombinant Human A-kinase anchor protein 9 protein (71-191AA)
Conjugation:
Unconjugated
Alternative Names:
A kinase (PRKA) anchor protein (yotiao) 9,A kinase (PRKA) anchor protein 9,AKAP 120-like protein,AKAP350,AKAP450,AKAP-9,AKAP9-BRAF fusion protein,A-kinase anchor protein 350 kDa,A-kinase anchor protein 450 kDa,A-kinase anchor protein 9,centrosome- and Golgi-localized PKN-associated protein,centrosome- and golgi-localized protein kinase N-associated protein,CG-NAP,HYPERION,kinase N-associated protein,LQT11,MU-RMS-40.16A,PPP1R45,PRKA9,protein hyperion,protein kinase A anchoring protein 9,Protein kinase A-anchoring protein 9,protein phosphatase 1, regulatory subunit 45,protein yotiao,YOTIAO.
Scaffolding protein that assembles several protein kinases and phosphatases on the centrosome and Golgi apparatus. Required to maintain the integrity of the Golgi apparatus (PubMed:10202149, PubMed:15047863). Required for microtubule nucleation at the cis-side of the Golgi apparatus (PubMed:15047863, PubMed:19242490). Required for association of the centrosomes with the poles of the bipolar mitotic spindle during metaphase (PubMed:25657325). In complex with PDE4DIP isoform 13/MMG8/SMYLE, recruits CAMSAP2 to the Golgi apparatus and tethers non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement (PubMed:27666745, PubMed:28814570). In complex with PDE4DIP isoform 13/MMG8/SMYLE, EB1/MAPRE1 and CDK5RAP2, contributes to microtubules nucleation and extension also from the centrosome to the cell periphery (PubMed:29162697).
