TACC3 Antibody

Catalog Number: ASB-OACA09967
Article Name: TACC3 Antibody
Biozol Catalog Number: ASB-OACA09967
Supplier Catalog Number: OACA09967
Alternative Catalog Number: ASB-OACA09967-100UG,ASB-OACA09967-50UG
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: ELISA, IF, IHC
Species Reactivity: Human
Immunogen: Recombinant Human Transforming acidic coiled-coil-containing protein 3 protein (133-268AA)
Conjugation: Unconjugated
Alternative Names: ERIC1,ERIC-1,maskin,Tacc4,transforming acidic coiled-coil-containing protein 3.
Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (PubMed:21297582, PubMed:23532825). May be involved in the control of cell growth and differentiation. May contribute to cancer (PubMed:14767476).
Clonality: Polyclonal
NCBI: 10460
Purity: >95%
Form: Liquid
Immunofluorescent analysis of HepG2 cells at dilution of 1:100 and Alexa Fluor 488-congu
Immunohistochemistry of paraffin-embedded human testis tissue at dilution of 1:100
Immunohistochemistry of paraffin-embedded human tonsil tissue at dilution of 1:100