FNIP1 Antibody
Catalog Number:
ASB-OACA09621
- Images (3)
| Article Name: | FNIP1 Antibody |
| Biozol Catalog Number: | ASB-OACA09621 |
| Supplier Catalog Number: | OACA09621 |
| Alternative Catalog Number: | ASB-OACA09621-100UG,ASB-OACA09621-50UG |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | ELISA, IF, IHC |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Folliculin-interacting protein 1 protein (221-508AA) |
| Conjugation: | Unconjugated |
| Alternative Names: | folliculin-interacting protein 1. |
| Acts as a co-chaperone of HSP90AA1. Inhibits the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. Facilitates the binding of client protein FLCN to HSP90AA1. Competes with the activating co-chaperone AHSA1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:27353360). May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways (PubMed:17028174). May regulate phosphorylation of RPS6KB1 (PubMed:18663353). |
| Clonality: | Polyclonal |
| NCBI: | 96459 |
| Purity: | >95% |
| Form: | Liquid |
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Immunofluorescent analysis of HepG-2 cells at dilution of 1:100 and Alexa Fluor 488- |
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Immunohistochemistry of paraffin-embedded human pancreatic tissue at dilution of 1:100 |
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Immunohistochemistry of paraffin-embedded human tonsil tissue at dilution of 1:100 |
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