NOP10 Antibody

Catalog Number: ASB-OACA06148
Article Name: NOP10 Antibody
Biozol Catalog Number: ASB-OACA06148
Supplier Catalog Number: OACA06148
Alternative Catalog Number: ASB-OACA06148-100UG,ASB-OACA06148-50UG
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: ELISA, IHC, WB
Species Reactivity: Human
Immunogen: Recombinant Human H/ACA ribonucleoprotein complex subunit 3 protein (1-64AA)
Conjugation: Unconjugated
Alternative Names: DKCB1,H/ACA ribonucleoprotein complex subunit 3,homolog of yeast Nop10p,NOLA3,NOP10 ribonucleoprotein homolog,NOP10P,nucleolar protein 10,nucleolar protein family A member 3,nucleolar protein family A, member 3 (H/ACA small nucleolar RNPs),snoRNP protein NOP10.
Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine (psi) residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.
Clonality: Polyclonal
NCBI: 55505
Purity: >95%
Form: Liquid
Immunohistochemistry of paraffin-embedded human breast cancer at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue at dilution of 1:100
Western blot
All lanes: NOP10 antibody at 4ug/ml
Lane 1: 293T whole cell lysat