PTPMT1 Antibody

Catalog Number: ASB-OACA05374
Article Name: PTPMT1 Antibody
Biozol Catalog Number: ASB-OACA05374
Supplier Catalog Number: OACA05374
Alternative Catalog Number: ASB-OACA05374-100UG,ASB-OACA05374-50UG
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: ELISA, IHC, WB
Species Reactivity: Human, Rat
Immunogen: Recombinant Human Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 protein (28-201AA)
Conjugation: Unconjugated
Alternative Names: DUSP23,MOSP,NB4 apoptosis/differentiation related protein,phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1,phosphoinositide lipid phosphatase,PLIP,PNAS-129,Protein-tyrosine phosphatase mitochondrial 1,PTEN-like phosphatase.
Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) (By similarity). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle (By similarity). Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production (By similarity). Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues (By similarity). Probably involved in regulation of insulin secretion in pancreatic beta cells (By similarity). May prevent intrinsic apoptosis, probably by regulating mitochondrial membrane integrity (PubMed:24709986).
Clonality: Polyclonal
NCBI: 114971
Form: Liquid
Immunohistochemistry of paraffin-embedded human colon cancer at dilution 1:100
Immunohistochemistry of paraffin-embedded human pancreatic tissue at dilution 1:100
Western blot
All lanes: PTPMT1 antibody at 12ug/ml
Lane 1: Mouse kidney tissue