ERO1B Antibody
Catalog Number:
ASB-OACA05233
- Images (3)
| Article Name: | ERO1B Antibody |
| Biozol Catalog Number: | ASB-OACA05233 |
| Supplier Catalog Number: | OACA05233 |
| Alternative Catalog Number: | ASB-OACA05233-100UG,ASB-OACA05233-50UG |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | ELISA, IHC, WB |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human ERO1-like protein beta protein (101-400AA) |
| Conjugation: | Unconjugated |
| Alternative Names: | endoplasmic oxidoreductin-1-like protein B,endoplasmic reticulum oxidoreductase beta,endoplasmic reticulum oxidoreductin-1-like protein B,Ero1beta,ERO1LB,ERO1-L-beta,ERO1-like beta,ERO1-like protein beta,oxidoreductin-1-L-beta. |
| Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Other protein disulfide isomerase family members can also be reoxidized, but at lower rates compared to P4HB, including PDIA2 (50% of P4HB reoxidation rate), as well as PDIA3, PDIA4, PDIA6 and NXNDC12 (<10%). Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. May be involved in oxidative proinsulin folding in pancreatic cells, hence may play a role in glucose homeostasis. |
| Clonality: | Polyclonal |
| NCBI: | 56605 |
| Purity: | >95% |
| Form: | Liquid |
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Immunohistochemistry of paraffin-embedded human pancreatic cancer at dilution of 1:100 |
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Immunohistochemistry of paraffin-embedded human pancreatic tissue at dilution of 1:100 |
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Western blot All lanes: ERO1B antibody at 3.2ug/ml Lane 1: MCF7 whole |
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