ARPIN Antibody

Catalog Number: ASB-OACA05225
Article Name: ARPIN Antibody
Biozol Catalog Number: ASB-OACA05225
Supplier Catalog Number: OACA05225
Alternative Catalog Number: ASB-OACA05225-100UG,ASB-OACA05225-50UG
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: ELISA, IHC, WB
Species Reactivity: Human
Immunogen: Recombinant Human Arpin protein (1-226AA)
Conjugation: Unconjugated
Alternative Names: arp2/3 inhibition protein,arpin,C15orf38,UPF0552 protein C15orf38.
Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex, the function is competetive with nucleation promoting factors. Participates in an incoherent feedforward loop at the lamellipodium tip where it inhibits the ARP2/2 complex in response to Rac signaling and where Rac also stimulates actin polymerization through the WAVE complex. Involved in steering cell migration by controlling its directional persistence.
Clonality: Polyclonal
NCBI: 348110
Purity: >95%
Form: Liquid
Immunohistochemistry of paraffin-embedded human colon cancer at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue at dilution of 1:100
Western blot
All lanes: ARPIN antibody at 0.5ug/ml+HepG-2 whole cell lysate
Goa