Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Yeast
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of Human EIF2B3
Alternative Names:
EIF-2B, EIF2Bgamma
The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.