ADGRE5 Antibody - C-terminal region
Catalog Number:
ASB-ARP63731_P050
- Images (3)
| Article Name: | ADGRE5 Antibody - C-terminal region |
| Biozol Catalog Number: | ASB-ARP63731_P050 |
| Supplier Catalog Number: | ARP63731_P050 |
| Alternative Catalog Number: | ASB-ARP63731_P050-25UL,ASB-ARP63731_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | IHC, WB |
| Species Reactivity: | Human |
| Alternative Names: | CD97, TM7LN1 |
| This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19. |



