TFRC Antibody - N-terminal region
Catalog Number:
ASB-ARP63718_P050
- Images (3)
| Article Name: | TFRC Antibody - N-terminal region |
| Biozol Catalog Number: | ASB-ARP63718_P050 |
| Supplier Catalog Number: | ARP63718_P050 |
| Alternative Catalog Number: | ASB-ARP63718_P050-25UL,ASB-ARP63718_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | IHC, WB |
| Species Reactivity: | Human |
| Alternative Names: | T9, TR, TFR, p90, CD71, TFR1, TRFR, IMD46 |
| TFRC is a cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system By similarity. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. |
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ARP63718_P050 |
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WB Suggested Anti-TFRC Antibody Titration: 1.0 ug/ml Positive Control: Fetal Heart |
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TFRC antibody - N-terminal region (ARP63718_P050) in Human Fetal heart using Western Blot |
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