HAS1 Antibody - N-terminal region
Catalog Number:
ASB-ARP63382_P050
- Images (3)
| Article Name: | HAS1 Antibody - N-terminal region |
| Biozol Catalog Number: | ASB-ARP63382_P050 |
| Supplier Catalog Number: | ARP63382_P050 |
| Alternative Catalog Number: | ASB-ARP63382_P050-25UL,ASB-ARP63382_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Canine, Guinea pig, Human, Mouse, Rat |
| Alternative Names: | HAS |
| Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is synthesized by membrane-bound synthase at the inner surface of the plasma membrane, and the chains are extruded through pore-like structures into the extracellular space. It serves a variety of functions, including space filling, lubrication of joints, and provision of a matrix through which cells can migrate. HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts. Changes in the serum concentration of HA are associated with inflammatory and degenerative arthropathies such as rheumatoid arthritis. In addition, the interaction of HA with the leukocyte receptor CD44 is important in tissue-specific homing by leukocytes, and overexpression of HA receptors has been correlated with tumor metastasis. |
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WB Suggested Anti-HAS1 Antibody Titration: 1.0 ug/ml Positive Control: THP-1 Whole Cell |
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Host: Rabbit Target Name: HAS1 Sample Tissue: Human HT1080 Whole Cell Antibody Dilution: 1ug/ml |
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HAS1 antibody - N-terminal region (ARP63382_P050) in Human THP-1 using Western Blot |
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