HLA-DMB Antibody - N-terminal region

Catalog Number: ASB-ARP63380_P050
Article Name: HLA-DMB Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP63380_P050
Supplier Catalog Number: ARP63380_P050
Alternative Catalog Number: ASB-ARP63380_P050-25UL,ASB-ARP63380_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Human, Rat
Alternative Names: RING7, D6S221E
HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 29kDa
NCBI: 3109
UniProt: P28068
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-HLA-DMB Antibody
Catalog Number: ARP63380_P050
Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue
Observed Staining: Plasma membrane in intercalated disk
Primary Antibody Concentration: 1:100
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
Host: Rabbit
Target Name: HLA-DMB
Sample Type: Human Placenta
Antibody Dilution: 1.0ug/ml
HLA-DMB antibody - N-terminal region (ARP63380_P050) in Human Placenta using Western Blot