MME Antibody - C-terminal region

Catalog Number: ASB-ARP63365_P050
Article Name: MME Antibody - C-terminal region
Biozol Catalog Number: ASB-ARP63365_P050
Supplier Catalog Number: ARP63365_P050
Alternative Catalog Number: ASB-ARP63365_P050-25UL,ASB-ARP63365_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat
Alternative Names: NEP, SFE, CD10, CALLA, CMT2T, SCA43
This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5 untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 83kDa
NCBI: 4311
UniProt: P08473
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-MME Antibody
Titration: 1.0 ug/ml
Positive Control: OVCAR-3 Whole Cell
Host: Mouse
Target Name: MME
Sample Tissue: Mouse Kidney
Antibody Dilution: 1ug/ml
MME antibody - C-terminal region (ARP63365_P050) in Human OVCAR-3 using Western Blot