VKORC1 Antibody - N-terminal region
Catalog Number:
ASB-ARP63330_P050
- Images (3)
| Article Name: | VKORC1 Antibody - N-terminal region |
| Biozol Catalog Number: | ASB-ARP63330_P050 |
| Supplier Catalog Number: | ARP63330_P050 |
| Alternative Catalog Number: | ASB-ARP63330_P050-25UL,ASB-ARP63330_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | IHC, WB |
| Species Reactivity: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N-terminal region of VKORC1 |
| Alternative Names: | VKOR, MST134, MST576, VKCFD2, EDTP308 |
| Vitamin K is essential for blood clotting but must be enzymatically activated. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins. The product of this gene encodes the enzyme that is responsible for reducing vitamin K 2,3-epoxide to the enzymatically activated form. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin, and it is the product of this gene that is sensitive to warfarin. In humans, mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and, in humans and rats, with warfarin resistance. Two pseudogenes have been identified on chromosome 1 and the X chromosome. Two alternatively spliced transcripts encoding different isoforms have been described. |
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Rabbit Anti-VKORC1 Antibody Catalog Number: ARP63330_P050 Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue Observed Staining: Cytoplasmic Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec |
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WB Suggested Anti-VKORC1 Antibody Titration: 1.0 ug/ml Positive Control: Fetal Brain |
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VKORC1 Antibody - N-terminal region (ARP63330_P050) in Human Fetal Brain using Western Blot |
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