HLA-DPB1 Antibody - middle region
Catalog Number:
ASB-ARP63264_P050
- Images (3)
| Article Name: | HLA-DPB1 Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP63264_P050 |
| Supplier Catalog Number: | ARP63264_P050 |
| Alternative Catalog Number: | ASB-ARP63264_P050-25UL,ASB-ARP63264_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | IHC, WB |
| Species Reactivity: | Canine, Human, Rabbit |
| Alternative Names: | DPB1, HLA-DP, HLA-DPB, HLA-DP1B |
| HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. |
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Rabbit Anti-HLA-DPB1 Antibody Catalog Number: ARP63264_P050 Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue Observed Staining: Cytoplasmic Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec |
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WB Suggested Anti-HLA-DPB1 Antibody Titration: 1.0 ug/ml Positive Control: ACHN Whole Cell |
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HLA-DPB1 antibody - middle region (ARP63264_P050) in Human ACHN using Western Blot |
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