Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Alternative Names:
CN5A, PDE5, CGB-PDE
This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sample Type: Human placental tissue Primary Antibody Dilution: 1:100Secondary Antibody: Goat anti rabbit-HRP Secondary Antibody Dilution: 1:10,000Color/Signal Descriptions: Brown: PDE5APurple: HaemotoxylinGene Name: PDE5ASubmitted by: Dr. Hiten D. Mistry and Anna Czajka, Kings College London, Lesia Kurlak, University of Nottingham