Prnp Antibody - middle region

Catalog Number: ASB-ARP63174_P050
Article Name: Prnp Antibody - middle region
Biozol Catalog Number: ASB-ARP63174_P050
Supplier Catalog Number: ARP63174_P050
Alternative Catalog Number: ASB-ARP63174_P050-25UL,ASB-ARP63174_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Goat, Human, Rat, Sheep
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Mouse Prnp
Alternative Names: P, S, PrP, PrPC, Sinc, CD230, PrPSc, Prn-i, Prn-p, PrP, AA960666, AI325101, prP27-30, prP33-35C
Prnp may play a role in neuronal development and synaptic plasticity, may be required for neuronal myelin sheath maintenance and may play a role in iron uptake and iron homeostasis. Prnp is a soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. It also provides Cu2+ or ZN2+ for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 28kDa
NCBI: 19122
UniProt: P04925
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-PRNP Antibody
Catalog Number: ARP63174_P050
Formalin Fixed Paraffin Embedded Tissue: Human Testis Tissue
Observed Staining: Plasma membrane and cytoplasm in Leydig cells
Primary Antibody Concentration: 1:100
Other Working Concentrations: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
Host: Rabbit
Target Name: Prnp
Sample Type: Mouse Kidney lysates
Antibody Dilution: 1.0ug/ml
Prnp Antibody - middle region (ARP63174_P050) in Mouse Kidney using Western Blot