GCK Antibody - N-terminal region
Catalog Number:
ASB-ARP61473_P050
- Images (3)
| Article Name: | GCK Antibody - N-terminal region |
| Biozol Catalog Number: | ASB-ARP61473_P050 |
| Supplier Catalog Number: | ARP61473_P050 |
| Alternative Catalog Number: | ASB-ARP61473_P050-25UL,ASB-ARP61473_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Sheep |
| Alternative Names: | GK, GLK, HK4, HHF3, HKIV, HXKP, LGLK, MODY2, PNDM1, FGQTL3 |
| Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI). |
|
|
WB Suggested Anti-GCK Antibody Titration: 1.0 ug/ml Positive Control: COLO205 Whole Cell |
|
|
Lanes: 1: 50 ug HEP3B lysate, 2: 50 ug HEP3B lysate Primary Antibody Dilution: 1:1000 Secondary Antibody: Anti-rabbit-HRP Secondary Antibody Dilution: 1:1000 Gene Name: GCK Submitted by: Received from annonymous |
|
|
GCK antibody - N-terminal region (ARP61473_P050) in Human COLO205 using Western Blot |
Product Guarantee and Expert Support
