Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat
Alternative Names:
MTTK, PEOB3, SCA31, MTDPS2
This gene encodes a deoxyribonucleoside kinase that specifically phosphorylates thymidine, deoxycytidine, and deoxyuridine. The encoded enzyme localizes to the mitochondria and is required for mitochondrial DNA synthesis. Mutations in this gene are associated with a myopathic form of mitochondrial DNA depletion syndrome.