PTPN6 Antibody - middle region

Catalog Number: ASB-ARP61398_P050
Article Name: PTPN6 Antibody - middle region
Biozol Catalog Number: ASB-ARP61398_P050
Supplier Catalog Number: ARP61398_P050
Alternative Catalog Number: ASB-ARP61398_P050-25UL,ASB-ARP61398_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Alternative Names: HCP, HCPH, SHP1, SHP-1, HPTP1C, PTP-1C, SHP-1L, SH-PTP1
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 65kDa
NCBI: 5777
UniProt: P29350
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-PTPN6 Antibody
Catalog Number: ARP61398_P050
Formalin Fixed Paraffin Embedded Tissue: Human Lymph Node Tissue
Observed Staining: Cytoplasm
Primary Antibody Concentration: 1:100
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
WB Suggested Anti-PTPN6 Antibody
Titration: 1.0 ug/ml
Positive Control: THP-1 Whole Cell
PTPN6 antibody - middle region (ARP61398_P050) in Human THP-1 using Western Blot