GPNMB Antibody - N-terminal region

Catalog Number: ASB-ARP44500_P050
Article Name: GPNMB Antibody - N-terminal region
Biozol Catalog Number: ASB-ARP44500_P050
Supplier Catalog Number: ARP44500_P050
Alternative Catalog Number: ASB-ARP44500_P050-25UL,ASB-ARP44500_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GPNMB
Alternative Names: NMB, HGFIN, PLCA3
GPNMB is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 60kDa
NCBI: 10457
UniProt: Q14956
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
HepG2
WB Suggested Anti-GPNMB Antibody Titration: 1 ug/ml
Positive Control: 293T cells lysate
GPNMB antibody - N-terminal region (ARP44500_P050) in Human 293T using Western Blot