UGT1A1 Antibody - middle region
Catalog Number:
ASB-ARP44294_T100
- Images (3)
| Article Name: | UGT1A1 Antibody - middle region |
| Biozol Catalog Number: | ASB-ARP44294_T100 |
| Supplier Catalog Number: | ARP44294_T100 |
| Alternative Catalog Number: | ASB-ARP44294_T100-25UL,ASB-ARP44294_T100-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Bovine, Equine, Human, Mouse, Porcine, Rabbit, Rat, Sheep |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human UGT1A1 |
| Alternative Names: | GNT1, UGT1, UDPGT, UGT1A, HUG-BR1, BILIQTL1, UDPGT 1-1 |
| UGT1A1 is a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. The preferred substrate of this enzyme is bilirubin, although it also has moderate activity with simple phenols, flavones, and C18 steroids.This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5 exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The preferred substrate of this enzyme is bilirubin, although it also has moderate activity with simple phenols, flavones, and C18 steroids. Mutations in this gene result in Crigler-Najjar syndromes types I and II and in Gilbert syndrome. |
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WB Suggested Anti-UGT1A1 Antibody Titration: 2.5ug/ml Positive Control: Human Liver |
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Host: Rabbit Target: UGT1A1 Positive control (+): Human liver (LI) Negative control (-): Human stomach (ST) Antibody concentration: 3ug/ml |
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UGT1A1 antibody - middle region (ARP44294_T100) in Human Liver using Western Blot |
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