HFE Antibody - C-terminal region

Catalog Number: ASB-ARP44285_P050
Article Name: HFE Antibody - C-terminal region
Biozol Catalog Number: ASB-ARP44285_P050
Supplier Catalog Number: ARP44285_P050
Alternative Catalog Number: ASB-ARP44285_P050-25UL,ASB-ARP44285_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HFE
Alternative Names: HH, HFE1, HLA-H, MVCD7, TFQTL2
HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in its gene.The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least eleven alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 28kDa
NCBI: 3077
UniProt: Q30201-4
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Human kidney
WB Suggested Anti-HFE Antibody Titration: 0.2-1 ug/ml
Positive Control: HepG2 cell lysate
HFE antibody - C-terminal region (ARP44285_P050) in Human HepG2 using Western Blot