MFN2 Antibody - C-terminal region

Catalog Number: ASB-ARP42420_P050
Article Name: MFN2 Antibody - C-terminal region
Biozol Catalog Number: ASB-ARP42420_P050
Supplier Catalog Number: ARP42420_P050
Alternative Catalog Number: ASB-ARP42420_P050-25UL,ASB-ARP42420_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MFN2
Alternative Names: HSG, MARF, CMT2A, CPRP1, CMT2A2, HMSN6A, CMT2A2A, CMT2A2B
MFN2 is a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. It is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke.This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 86kDa
NCBI: 9927
UniProt: O95140
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-MFN2 Antibody
Catalog Number: ARP42420_P050
Formalin Fixed Paraffin Embedded Tissue: Human Heart Tissue
Observed Staining: Cytoplasm in cardiomyocytes
Primary Antibody Concentration: 1:100
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
WB Suggested Anti-MFN2 Antibody Titration: 0.2-1 ug/ml
Positive Control: 293T cell lysate
MFN2 antibody - C-terminal region (ARP42420_P050) in Human 293T using Western Blot