SPI1 Antibody - middle region

Catalog Number: ASB-ARP38241_P050
Article Name: SPI1 Antibody - middle region
Biozol Catalog Number: ASB-ARP38241_P050
Supplier Catalog Number: ARP38241_P050
Alternative Catalog Number: ASB-ARP38241_P050-25UL,ASB-ARP38241_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Canine, Equine, Guinea pig, Human, Mouse, Porcine, Rat, Zebrafish
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SPI1
Alternative Names: OF, PU.1, SFPI1, SPI-1, SPI-A
SPI1 is known to collaborate with multiple transcription factors and to regulate expression of immunoglobulin genes. Lack of SPI1 expression is associated with defective immunoglobulin transcription in Hodgkin and Reed-Sternberg cells of classical Hodgkin disease. This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 31kDa
NCBI: 6688
UniProt: P17947
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-SPI1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human Muscle
Host: Rabbit
Target: SPI1
Positive control (+): U937 Cell Lysate (N31)
Negative control (-): A549 Cell Lysate (N03)
Antibody concentration: 3ug/ml
Host: Rabbit
Target Name: SPI1
Sample Tissue: Human RPMI 8226 Whole Cell
Antibody Dilution: 3ug/ml
SPI1 antibody - middle region (ARP38241_P050) in Human Muscle using Western Blot