RUNX2 Antibody - middle region

Catalog Number: ASB-ARP36678_T100
Article Name: RUNX2 Antibody - middle region
Biozol Catalog Number: ASB-ARP36678_T100
Supplier Catalog Number: ARP36678_T100
Alternative Catalog Number: ASB-ARP36678_T100-25UL,ASB-ARP36678_T100-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: WB
Species Reactivity: Bovine, Canine, Guinea pig, Human, Mouse, Rabbit, Rat
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RUNX2
Alternative Names: CCD, AML3, CCD1, CLCD, OSF2, CBFA1, OSF-2, PEA2aA, PEBP2aA, CBF-alpha-1
RUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis, acting as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants, encoding different protein isoforms, result from alternate promoter use as well as alternate splicing.
Clonality: Polyclonal
Concentration: 1.0 mg/ml
Molecular Weight: 57kDa
NCBI: 860
UniProt: Q13950
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
WB Suggested Anti-RUNX2 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:1562500
Positive Control: Jurkat cell lysate
Host: Rabbit
Target Name: RUNX2
Sample Tissue: Human Jurkat
Antibody Dilution: 1.0ug/ml
Host: Rabbit
Target: RUNX2
Positive control (+): Hela (HL)
Negative control (-): Human liver (LI)
Antibody concentration: 0.2ug/ml
RUNX2 antibody - middle region (ARP36678_T100) in Human Jurkat using Western Blot