KLF6 Antibody - N-terminal region

Article Name:	KLF6 Antibody - N-terminal region
Biozol Catalog Number:	ASB-ARP35640_P050
Supplier Catalog Number:	ARP35640_P050
Alternative Catalog Number:	ASB-ARP35640_P050-25UL,ASB-ARP35640_P050-100UL
Manufacturer:	Aviva
Host:	Rabbit
Category:	Proteine/Peptide
Application:	WB
Species Reactivity:	Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat, Zebrafish
Immunogen:	The immunogen is a synthetic peptide directed towards the N terminal region of human KLF6
Alternative Names:	GBF, ZF9, BCD1, CBA1, CPBP, PAC1, ST12, COPEB

KLF6 is a nuclear protein that has three zinc fingers at the end of its C-terminal domain, a serine/threonine-rich central region, and an acidic domain lying within the N-terminal region. The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements. The central region might be involved in activation or posttranslational regulatory pathways, and the acidic N-terminal domain might play an important role in the process of transcriptional activation. It is capable of activating transcription approximately 4-fold either on homologous or heterologous promoters. KLF6 may participate in the regulation and/or maintenance of the basal expression of pregnancy-specific glycoprotein genes and possibly other TATA box-less genes.This gene encodes a nuclear protein that has three zinc fingers at the end of its C-terminal domain, a serine/threonine-rich central region, and an acidic domain lying within the N-terminal region. The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements. The central region might be involved in activation or posttranslational regulatory pathways, and the acidic N-terminal domain might play an important role in the process of transcriptional activation. It is capable of activating transcription approximately 4-fold either on homologous or heterologous promoters. The DNA binding and transcriptional activity of this protein, in conjunction with its expression pattern, suggests that this protein may participate in the regulation and/or maintenance of the basal expression of pregnancy-specific glycoprotein genes and possibly other TATA box-less genes. Two transcript variants encoding the same protein have been found for this gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-731 BM544849.1 20-750 732-1504 BC000311.2 669-1441 1505-1598 BC004301.1 1440-1533

Clonality:	Polyclonal
Concentration:	0.5 mg/ml
Molecular Weight:	32kDa
NCBI:	1316
UniProt:	Q99612
Form:	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

	Host: Rabbit Target Name: KLF6 Sample Tissue: Human Fetal Liver Antibody Dilution: 1.0ug/ml
	WB Suggested Anti-KLF6 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human Stomach
	Host: Mouse Target Name: KLF6 Sample Tissue: Mouse Pancreas Antibody Dilution: 1ug/ml
	KLF6 antibody - N-terminal region (ARP35640_P050) in Human Fetal Liver using Western Blot