LIG4 Antibody - N-terminal region
Catalog Number:
ASB-ARP34122_T100
- Images (4)
| Article Name: | LIG4 Antibody - N-terminal region |
| Biozol Catalog Number: | ASB-ARP34122_T100 |
| Supplier Catalog Number: | ARP34122_T100 |
| Alternative Catalog Number: | ASB-ARP34122_T100-25UL,ASB-ARP34122_T100-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | IHC, WB |
| Species Reactivity: | Bovine, Canine, Equine, Guinea pig, Human, Mouse, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human LIG4 |
| Alternative Names: | LIG4S |
| LIG4 encodes a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. This protein is essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X-ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA-dependent protein kinase (DNA-PK). Both XRCC4 and DNA-PK are known to be required for NHEJ. The crystal structure of the complex formed by this protein and XRCC4 has been resolved. Defects in this gene are the cause of LIG4 syndrome. |
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Human Pancreas |
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WB Suggested Anti-LIG4 Antibody Titration: 1.25ug/ml Positive Control: HepG2 cell lysate |
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Host: Rabbit Target Name: LIG4 Sample Tissue: Human Fetal Liver Antibody Dilution: 1.0ug/ml |
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LIG4 antibody - N-terminal region (ARP34122_T100) in Human Fetal Liver using Western Blot |
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